Peter Parker is a socially unpopular high-school boy who lives with his Uncle Ben and Aunt May after his parents left him when he was very young for reasons unknown. He finds a clue to their disappearance in the form of his father's suitcase and his journey for an explanation takes him to Oscorp, the weapons manufacturer of New York, and the lab of his father's ex-business partner Dr. Curt Connors who offers him that explanation. Along his journey, the alter-egos of Connors (The Lizard) and Parker (Spider-Man) collide in a continuous battle of superpowers and Parker's feelings for his first high-school crush Gwen Stacy, whose father is a Police Captain with officers all over the city looking for Parker, intensify.
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