The comedian was promoting the forthcoming season of Check It Out! with Dr. Steve Brule, a TV series on U.S. network Adult Swim, in which he interviews guests about different facets of living, all while portraying the socially-awkward doctor, and he brought the character to life at Sasquatch!, bumbling through a prayer before welcoming Diplo's dance act to the stage.

Reilly may have appeared to be an odd choice to open Major Lazer's set, but his show co-creator, Eric Wareheim, has also directed a number of the band's videos.

Earlier in the day, the Wreck-It Ralph star had also addressed audiences to introduce Nathaniel Rateliff & The Night Sweats to fans, before showing off his dance moves during their set.

Reilly is no stranger to the four-day festival in Quincy - he performed as a musician there in 2012.

Meanwhile, the annual event wasn't without drama over the weekend. On Sunday afternoon (29May16), officials had to temporarily shut down the main stage at Gorge Amphitheatre due to high winds, prompting them to cancel performances from Saint Motel and Houndmouth, while local band Tacocat had their set moved to the El Chupacabra stage.

The main platform was reopened hours later, in time for top acts Alabama Shakes and The Cure to perform for fans.

The weather also didn't help a nearby wildfire, which caused authorities in Grant County to evacuate a camping area just three miles (4.8 kilometres) away from the Sasquatch! venue. The festival itself was not affected by the fire, which was blowing in the opposite direction of the event, but the heavy smoke could be seen by concert-goers onsite.