The song, which was co-written by Missy and producer Timbaland, was released on 10 December 1996 and appeared on the late singer's second studio album of the same name.
Aaliyah, real name Aaliyah Dana Haughton, died at the age of 22 in a 2001 plane crash in the Bahamas, where she had travelled to shoot the video for her song Rock the Boat.
On Saturday (10Dec16), Missy took to social media to remember her friend and collaborator with a touching message.
"Time flies! And there's still not a day that goes by that u aren't inspiring new artist (sic) with your TIMELESS music & style! U will never be forgotten Aaliyah (Babygirl)," she wrote in a post on Instagram accompanied by a still of Aaliyah from a video of the star taken from the track One in a Million.
The song became a hit on the Billboard R&B charts, reaching number one on the R&B Airplay Chart for six weeks, and was a major milestone in the careers of both Missy and Timbaland. The album of the same name debuted at twenty on the Billboard 200 chart and it was certified double Platinum in June 1997.
Missy is not the only artist to remember the influence of Aaliyah on R&B and hip hop.
In 2010, Hotline Bling rapper Drake penned a letter in her honour, writing: "I remember getting the news that you had passed and it connected with my heart like a clean shot from Muhammad Ali. I was crushed. Not only was I one of your biggest fans but I was truly in love with you."
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