Slash's wife has reportedly left him.

The 49-year-old musician has been issued with an ultimatum by spouse Perla Hudson - who unexpectedly flew out to Hawaii at the weekend with their sons London, 12, and 10-year-old Cash - to sort out their problems by the beginning of 2015 or their 13-year marriage is over for good.

The couple have had many arguments during their marriage but one source told website TMZ ''this time it's different''.

While Perla is confiding in friends that she and Slash - whose real name is Saul Hudson - have separated, she hasn't made any legal moves to officially end their marriage.

This isn't the first time the couple's marriage has hit the rocks.

In 2010, Slash filed for divorce from his wife - who is also his manager and runs all his companies - citing irreconcilable differences and seeking joint custody of their sons.

Though that split was described as ''extremely acrimonious'', the pair reconciled and the 'Welcome to the Jungle' musician called off the legal proceedings just two months later.

A spokesperson for the rocker has yet to comment on the separation claims.