The guitarist's instrument, an orange Epiphone, went missing while it was being shipped between New York and Los Angeles, and the rockers have asked fans to stay alert and pass on any information that could help locate it.
In a message posted on the band's Facebook.com page, they write, "Hello Friends, In a bit of unfortunate news, we've recently learned that Nick's beloved Epiphone guitar has gone missing while being shipped from NYC to LA... We ask that you join us in keeping an eye out for it. It goes without saying how bummed he is that it's gone missing. If you have any info at all about the guitar - perhaps see it in a pawn shop or on eBay - please send an email... We deeply appreciate the extra eyes and ears."
The band posted a detailed description of the guitar and and an email address to which fans can send tips.
The Strokes are believed to be on the verge of mounting a comeback two years after the release of their last album, 2013's Comedown MAChine. They have played a handful of dates in recent months and are said to be back in the studio working on a new record.