The British DJ's latest track, featuring Bruno Mars, was also the most streamed track of the week after being played more than 2.45 million times.
Mark Ronson's domination of the U.K. music scene continues as he earns the No.1 single with his latest number 'Uptown Funk' featuring Bruno Mars for the fifth straight week with combined sales figures of nearly 126,000.
Ronson earned this week's U.K. No.1 single with his track 'Uptown Funk'
The duo's soul-funk track has now achieved the most weeks at the top of the chart since Robin Thicke's 'Blurred Lines' in 2013.
'Uptown Funk' was also the most streamed track of the week after being played more than 2.45 million times in the last seven days, beating the likes of Ed Sheeran's 'Thinking Out Loud' (1.56m), Hozier's 'Take Me To Church' (1.56m) and Philip George's 'Wish You Were Mine' (1.17m).
Phillip George's 'Wish You Were Mine,' which samples the Stevie Wonder song 'My Cherie Amour,' lands at the No.2 spot and coming in third is Hozier's 'Take Me To Church.' Taking this week's fourth position is Olly Murs and Demi Lovato's duet 'Up,' and rounding off this week's top five is the hugely popular Ed Sheeran track 'Thinking Out Loud.'
Earlier this week Ronson released his fourth studio album 'Uptown Special,' which he dedicated to the late Amy Winehouse. They both collaborated on the singer's 'Back To Black' album and a cover of The Zutons' 'Valerie' before her tragic death in 2011. The producer posted a handwritten note on Twitter, which read, "Although I wish you were still here, I'm always thinking of you, inspired by you and your music lives on in myself and everyone who ever felt it."
Below are this week's U.K. top ten singles, complied by The Official Charts Company:
1. Mark Ronson - Uptown Funk (ft. Bruno Mars)
2. Phillip George - Wish You Were Mine
3. Hozier - Take Me To Church
4. Olly Murs - Up (ft. Demi Lovato)
5. Ed Sheeran - Thinking Out Loud
6. Taylor Swift - Blank Space
7. Alesso - Heroes
8. Ben Haenow - Something I Need
9. Tchami ft Kaleem Taylor - Promesses
10. Sam Smith - Like I Can