Tom Hanks' 58-year-old wife has undergone a double mastectomy and reconstructive surgery after discovering she had invasive lobular carcinoma.

Announcing the news, Wilson thanked her friends and family for their support - and now it seems those who were sworn to secrecy have flooded Twitter and Instagram to offer the actress their best wishes.

Vardalos, who shot to fame in Wilson's film My Big Fat Greek Wedding, writes, "I love Rita", while cancer survivor Applegate adds, "Sweet beautiful powerful Rita!!! Loving you so much!"

Making her announcement on Tuesday, Wilson assured fans that she was determined to beat cancer, stating, "I am recovering and most importantly, expected to make a full recovery. Why? Because I caught this early, have excellent doctors and because I got a second opinion."

Other tributes to the actress have been posted by newswoman Katie Couric, Rosie O'Donnell and singers Chely Wright and Sara Bareilles.