Steven Soderbergh’s Side Effects stars Channing Tatum and Rooney Mara and is another fine example of Soderbergh’s masterful storytelling. Fans of Soderbergh will do well to relish this one as it may be his last. The director has said that he’s tired of making films now and may well make Side Effects his last effort. The movies has garnered a slew of great reviews and could well out to be the most respected role that Channing Tatum has been attached to, for quite some time.

Side Effects is a thriller, telling the tale of a suicidal wife, a husband just out of jail, an under-pressure psychiatrist and the troubles with personality-suppressing drugs. Performances from Catherine Zeta Jones and Jude Law supplement those of the central characters. As is typical with Soderbergh’s movies (Traffic, A Scanner Darkly), the plot is many-faceted and eventually, the dramatic potential of the movie explodes. Kenneth Turan, writing for Los Angeles Times explains “It would ruin the fun to detail exactly what kind of hell, but rest assured this top-notch cast has great fun working out all the fiendish ramifications of this potboiler plot. If this does prove to be Soderbergh's final film — and I wouldn't hold my breath — he picked a heck of a one to go out on.

The movie has racked up a highly respectable score of 82% on Rotten Tomatoes – usually a decent indicator of how a film will fare. Side Effects is in US movie theaters this weekend.

Watch the trailer for Side Effects: