Giuliana Rancic is considering adopting a baby.

The E! News anchor, who has son Duke, two, with husband Bill Rancic, was devastated when their surrogate, Delphine, miscarried their second child earlier this year, but still hopes to have a big family.

Asked if they would ever adopt, the 40-year-old star said: ''Absolutely! We're not looking at it now, but if one day we're settled in the suburbs of Chicago, why not have a bunch of happy kids running around having a great life?''

The reality TV star hopes that Delphine will agree to carry another child for them in the future, as she is unable to get pregnant due to medication she is still on after successfully beating breast cancer in 2011.

She added to In Touch magazine: ''Delphine had great pregnancies with her two sons and she had an amazing pregnancy with Duke. When she's ready [to try again,] we're 100 per cent ready.

''We'd like to wait until things slow down a bit, but if Delphine is willing to do it this year, that's great.

''I'd love a little girl.''