The 'Someone Like You' hitmaker - who recently was forced to cancel her American tour due to illness - will compete in the categories Artist of the Year, Favourite Female Artist, Favourite Adult Contemporary Artist and Favourite Album for '21'.
The 39th annual American Music Awards will be held November 20 at the Nokia Theatre in Los Angeles.
Full list of American Music Awards nominations:
Pop or Rock Music: Favourite Female Artist
Pop or Rock Music: Favourite Male Artist
Pop or Rock Music: Favourite Band, Duo or Group
Pop or Rock Album
Adele - '21'
Rihanna - 'Loud'
Lady Gaga - 'Born This Way'
Rap/Hip-Hop Music: Favourite Artist
Lil Wayne - 'Tha Carter IV'
The Throne - 'Watch the Throne'
Nicki Minaj - 'Pink Friday'
Soul/R&B Music: Favourite Male Artist
Soul/R&B Music: Favourite Female Artist
Chris Brown - 'F.A.M.E.'
Rihanna - 'Loud '
BeyoncÃ© - '4'
Alternative Rock Music: Favourite Artist
Mumford & Sons
Adult Contemporary Music: Favourite Artist
Latin Music: Favourite Artist
Country Music: Favourite Female Artist
Country Music: Favourite Male Artist
Country Music: Favourite Band, Duo or Group
Country Music: Favourite Album
Jason Aldean - 'My Kinda Party'
Taylor Swift - 'Speak Now'
The Band Perry - 'The Band Perry'
Artist of the Year